Serodiagnosis of gut tuberculosis.
Article
in English
| IMSEAR
| ID: sea-91893
ABSTRACT
The efficacy of enzyme-linked immunosorbent assay (ELISA) in the diagnosis of gut tuberculosis was evaluated. The study included 95 patients with gut tuberculosis, 40 with pulmonary tuberculosis, 25 with non-tubercular intestinal diseases and 40 healthy controls. Mantoux response and antibody titre against PPD using ELISA were studied. The ELISA sensitivity in gut tuberculosis was 80% and in pulmonary tuberculosis 90%. It was also positive in 12% of patients with non-tubercular intestinal diseases and 5% of healthy controls. The sensitivity of Mantoux test in gut (77%) and pulmonary (84%) tuberculosis was comparable to that of ELISA. However, Mantoux test lacked diagnostic significance due to high positivity in non-tubercular disease patients (55%) and healthy controls (56%), whereas ELISA was highly specific (93%) for the diagnosis of gut tuberculosis.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Tuberculosis, Gastrointestinal
/
Tuberculosis, Pulmonary
/
Humans
/
Enzyme-Linked Immunosorbent Assay
/
Tuberculin Test
/
Antibodies, Bacterial
/
Mycobacterium tuberculosis
Language:
English
Year:
1990
Type:
Article
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