2-CdA in the treatment of hairy cell leukaemia.
Article
in English
| IMSEAR
| ID: sea-91940
ABSTRACT
INTRODUCTION:
Hairy cell leukaemia (HCL) is a rare lymphoproliferative disorder. Treatment options available are splenectomy, interferon, DCF and 2-CdA. 2-CdA is considered to have curative potential as proved by the other studies.METHODS:
We gave 2-CdA in a dose of 0.09/kg/day as a continuous infusion in sixteen patients of hairy cell leukaemia.RESULTS:
Three patients developed neutropenia post transfusion. At the end of three months all patients were in remission. Two patients relapsed at the median follow-up of 15 months.CONCLUSION:
2-CdA in HCL can achieve complete remission, prolonged survival and care as well.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Female
/
Humans
/
Male
/
Leukemia, Hairy Cell
/
2-Chloroadenosine
/
Deoxyadenosines
/
Survival Rate
/
Treatment Outcome
/
Adult
/
Middle Aged
Language:
English
Year:
2001
Type:
Article
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