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Cranial irradiation--an unusual cause for diabetes insipidus.
Article in English | IMSEAR | ID: sea-94390
ABSTRACT
Central diabetes insipidus frequently occurs due to tumours in the region of pituitary or hypothalamus or following surgical trauma to these regions. Rarely it has been reported following cranial irradiation. We report the case of a middle aged woman who underwent surgical removal of a frontal capillary hemangioblastoma and received cranial irradiation. She presented ten months later with features of diabetes insipidus which was confirmed to be of central origin. She responded well to desmopressin nasal spray. Radiation induced damage to the hypothalmo-pituitary axis presents usually with anterior pituitary hormone deficiencies, most commonly that of growth hormone. Presentation as central diabetes insipidus is very uncommon.
Subject(s)
Full text: Available Index: IMSEAR (South-East Asia) Main subject: Female / Humans / Cerebellar Neoplasms / Follow-Up Studies / Cranial Irradiation / Hemangioblastoma / Risk Assessment / Deamino Arginine Vasopressin / Diabetes Insipidus / Middle Aged Type of study: Etiology study / Observational study / Prognostic study / Risk factors Language: English Year: 2000 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Female / Humans / Cerebellar Neoplasms / Follow-Up Studies / Cranial Irradiation / Hemangioblastoma / Risk Assessment / Deamino Arginine Vasopressin / Diabetes Insipidus / Middle Aged Type of study: Etiology study / Observational study / Prognostic study / Risk factors Language: English Year: 2000 Type: Article