Prognosis and management of membraneous nephropathy.
Article
in English
| IMSEAR
| ID: sea-95307
ABSTRACT
Patients of idiopathic membranous nephropathy (MGN) were randomly assigned to received steroid and cyclophosphamide every other month (Gr-I) and steroid alone (Gr-II). Of 36 patients in Gr.I, 33 patients achieved complete remissions, 2 had relapsing course with remission on further courses of therapy and only one has reached end stage renal failure. In contrast, of the 35 patients in Gr. II, 15 (P < 0.001) achieved complete remission, 7 are in partial remission, 5 have no response, another 5 have deterioration of renal function of which two required dialysis, and 3 have relapsing course after the initial remission. Mean follow up period was 46 +/- 10.2 months. We conclude that steroid and cyclophosphamide every other month is highly effective in achieving remission in patients with membranous nephropathy.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Prognosis
/
Aged
/
Female
/
Humans
/
Male
/
Drug Administration Schedule
/
Prednisolone
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Glomerulonephritis, Membranous
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Follow-Up Studies
/
Adolescent
Type of study:
Controlled clinical trial
/
Observational study
/
Prognostic study
Language:
English
Year:
1993
Type:
Article
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