Platelet function in acute leukemias.
Article
in English
| IMSEAR
| ID: sea-95322
ABSTRACT
Bleeding time, clot retraction, platelet factor 3 availability and platelet aggregation in response to ADP, epinephrine, collagen and ristocetin were studied in 13 cases of acute leukemia which included 5 cases of acute myeloid leukemia, 2 of chronic myeloid leukemia in blast crisis and 6 of acute lymphoblastic leukemia. More than one abnormality was seen in all the patients. Defects in bleeding time, clot retraction and platelet factor 3 availability were encountered in 43% of cases. Platelet aggregation responses to all the reagents were significantly impaired. There was, however, no consistency in the pattern of the defects.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Platelet Function Tests
/
Blood Platelets
/
Humans
/
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
/
Leukemia, Myeloid, Acute
/
Blast Crisis
/
Platelet Aggregation
/
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Language:
English
Year:
1993
Type:
Article
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