Incidence of tuberculosis among patients receiving treatment with oral corticosteroids.
Article
in English
| IMSEAR
| ID: sea-95395
ABSTRACT
OBJECTIVES:
To study the incidence and pattern of tuberculosis in patients taking systemic corticosteroids (CS).METHODS:
Seventy seven patients taking oral CS for various respiratory diseases and eighty patients suffering from similar diseases but not receiving steroids were followed up for one year to study the incidence of tuberculosis.RESULTS:
Five patients (6.5%) receiving CS developed tuberculosis as against none amongst the controls (p < 0.05). Of these, three patients had sputum positive pulmonary tuberculosis and one each had sputum negative pulmonary tuberculosis and tubercular meningitis. All patients were treated with standard anti-tubercular therapy; four patients improved whereas one died due to complications of disease.CONCLUSION:
Systemic CS therapy causes a significant increase in incidence of tuberculosis.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Respiratory Tract Diseases
/
Tuberculosis, Pulmonary
/
Female
/
Humans
/
Male
/
Case-Control Studies
/
Incidence
/
Administration, Oral
/
Prospective Studies
/
Adrenal Cortex Hormones
Type of study:
Incidence study
/
Observational study
/
Prognostic study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Year:
2000
Type:
Article
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