Genetic epidemiology of the three predominant abnormal hemoglobins in India.
Article
in English
| IMSEAR
| ID: sea-95582
ABSTRACT
Hemoglobinopathies in India are Important public health problems. Of the several abnormal of hemoglobin molecules, there are three variants, viz. Sickle cell, hemoglobin E and hemoglobin D which are predominantly prevalent in India. The cumulative gene frequencies of these hemoglobins have been found to be 5.35% in India. The average gene frequency of sickle cell and hemoglobin D in India has been observed to be 4.3% and 0.86%, respectively. In the North Eastern region of India, the gene frequency of hemoglobin E is 10.9%. Gene frequencies and spatial distribution of the predominant abnormal hemoglobins in India have been discussed in variance with the previous generalisations.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Humans
/
Hemoglobin E
/
Hemoglobin, Sickle
/
Hemoglobins, Abnormal
/
Ethnicity
/
Prevalence
/
Molecular Epidemiology
/
Adult
/
Gene Frequency
/
Hemoglobinopathies
Type of study:
Prevalence study
/
Screening study
Country/Region as subject:
Asia
Language:
English
Year:
1996
Type:
Article
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