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Management of carcinoma anal canal with combination chemotherapy and concurrent radiotherapy.
J Indian Med Assoc ; 1996 Feb; 94(2): 53-4, 57
Article in English | IMSEAR | ID: sea-98180
ABSTRACT
Results of 21 cases of squamous cell carcinoma of anal canal treated by continuous infusion of 5-fluorouracil 1000 mg/sqm for 4 days and mitomycin-C 15 mg/sqm on 1st day by i.v. route with concurrent external beam radiotherapy of 42 Gy from 1st day of chemotherapy were analysed. Out of 21 patients, 16(76.19%) achieved complete remission, 3 (14.28%) partial remission and 2 (9.52%) cases did not respond at all. On follow-up, 7 (33.33%) histopathological positive cases needed abdominoperineal resection with good recovery. After 2 years of follow-up 14 (66.67%) cases were free from the disease and 3 (14.28%) were alive with the disease. The median duration of follow-up was 36 months.
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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Anus Neoplasms / Remission Induction / Aged / Female / Humans / Male / Carcinoma, Squamous Cell / Antineoplastic Combined Chemotherapy Protocols / Survival Analysis / Follow-Up Studies Type of study: Observational study / Prognostic study Language: English Journal: J Indian Med Assoc Year: 1996 Type: Article

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Full text: Available Index: IMSEAR (South-East Asia) Main subject: Anus Neoplasms / Remission Induction / Aged / Female / Humans / Male / Carcinoma, Squamous Cell / Antineoplastic Combined Chemotherapy Protocols / Survival Analysis / Follow-Up Studies Type of study: Observational study / Prognostic study Language: English Journal: J Indian Med Assoc Year: 1996 Type: Article