Humoral immune responses in different clinical forms of tuberculosis.
J Indian Med Assoc
;
2001 Aug; 99(8): 424, 426-7, 440
Article
in English
| IMSEAR
| ID: sea-98888
ABSTRACT
To assess the antibody responses in different clinical forms of tuberculosis in an attempt to ascertain the specificity of such a response, so that it may be used as a diagnostic tool, 93 tuberculosis cases and 62 normal healthy controls were included in the study. All the cases were diagnosed as tuberculosis by clinical picture including radiological findings, blood picture, fine needle aspiration cytology (FNAC) or histopathological features, sputum examination or urine culture for acid-fast bacilli. IgM and IgG antibodies in the cases and controls were detected by ELISA using A60 antigen from M. bovis and compared with common diagnostic parameters of tuberculosis like presence of acid-fast bacilli in smear and tuberculin response. Antibody responses with A60 antigen has not been found to be specific and often failed to detect a new case.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Tuberculosis
/
Severity of Illness Index
/
Female
/
Humans
/
Male
/
Immunoglobulin G
/
Immunoglobulin M
/
Enzyme-Linked Immunosorbent Assay
/
Case-Control Studies
/
Child
Type of study:
Diagnostic study
/
Etiology study
/
Incidence study
/
Observational study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
J Indian Med Assoc
Year:
2001
Type:
Article
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