Unusual association of Kikuchi's disease and dengue virus infection evolving into systemic lupus erythematosus.
J Indian Med Assoc
;
2000 Jul; 98(7): 391-3
Article
in English
| IMSEAR
| ID: sea-99569
ABSTRACT
Kikuchi's disease is a histologically alarming self-limiting condition typically affecting the lymph nodes of young females. A 13-year-old girl was presented with fever, skin rash and cervical lymphadenopathy. On examination she was found febrile, mild pallor was present and she had lymphadenopathy. Liver was palpable. Cervical lymph node biopsy showed histiocytic necrotising lymphadenitis (Kikuchi's disease). Dengue virus serology for IgG blot showed evidence of seroconversion in serial samples. She was treated with antibiotics and fluconazole and cyclosporin A. During hospitalisation she developed retinal vasculitis. She was reviewed after one month and showed rashes of subacute cutaneous lupus erythematosus. This case can be described to be a triggering event by dengue viral infection causing abnormal immune response leading initially to Kikuchi's disease and later on to systemic lupus erythematosus.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Female
/
Humans
/
Follow-Up Studies
/
Adolescent
/
Histiocytic Necrotizing Lymphadenitis
/
Dengue
/
India
/
Lupus Erythematosus, Systemic
Type of study:
Observational study
/
Prognostic study
/
Risk factors
Country/Region as subject:
Asia
Language:
English
Journal:
J Indian Med Assoc
Year:
2000
Type:
Article
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