Reactions and their management.
J Indian Med Assoc
;
2004 Dec; 102(12): 688-90, 692, 694
Article
in English
| IMSEAR
| ID: sea-99955
ABSTRACT
The uneventful response to chemotherapy in leprosy is marked by clinically disturbing episodes encountered in 20-30% of patients and these phenomena are called "reactions". Generally they are classified as reversal reaction (type-1) and erythema nodosum leprosum (type-2). The cutaneous menifestations are (1) Type-2 reactions in LL, BL types constituting erythema nodosum leprosum, erythema multiforme, erythema necroticans, subcutaneous nodules, lepromatous exacerbation. (2) Type-1 reactions in borderline and tuberculoid leprosy. The other manifestations include Acute neuritis, lymphadenitis, arthritis, oedema of the hands and feet, ocular lesions, etc. Sequelae of reactions are Paralytic deformities, non-paralytic deformities, extensive scarring and renal damage. A simple guideline to identify the risk-prone cases has been narrated. Prednisolone in standard dosage schedule as recommended by WHO is now being widely used in control programmes.
Full text:
Available
Index:
IMSEAR (South-East Asia)
Main subject:
Paralysis
/
Arthritis
/
Skin
/
Thalidomide
/
Humans
/
Prednisolone
/
Cicatrix
/
Treatment Outcome
/
Clofazimine
/
Dose-Response Relationship, Drug
Type of study:
Practice guideline
Language:
English
Journal:
J Indian Med Assoc
Year:
2004
Type:
Article
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