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Successful Early Lamotrigine and Aripiprazole Augmentation of Clomipramine in Severe Obsessive-compulsive Disorder
Clinical Psychopharmacology and Neuroscience ; : 604-608, 2023.
Article in English | WPRIM | ID: wpr-1000093
ABSTRACT
Lamotrigine and aripiprazole have shown efficacy as augmentation agents of serotonin reuptake inhibitors for treatment-resistant obsessive-compulsive disorder (OCD). To date, the efficacy of lamotrigine/aripiprazole augmentation has not been reported in OCD treatment. Herein, we report the case of a 37-year-old male with severe OCD and comorbid depression whose symptoms markedly improved after low-dose lamotrigine/aripiprazole augmentation to clomipramine.Our report suggests that early glutamatergic/antipsychotic augmentation contributes to rapid remission of OCD symptoms.
Full text: Available Index: WPRIM (Western Pacific) Language: English Journal: Clinical Psychopharmacology and Neuroscience Year: 2023 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: English Journal: Clinical Psychopharmacology and Neuroscience Year: 2023 Type: Article