Trends in Antibiotic Use in a Single University Hospital / 병원감염관리
Korean Journal of Nosocomial Infection Control
;
: 44-50, 2013.
Article
in Korean
| WPRIM
| ID: wpr-100019
ABSTRACT
BACKGROUND:
The aim of this study was to evaluate antibiotic consumption by adult patients at a single university hospital in Korea between 2001 and 2012.METHODS:
We used the 2004 World Health Organization Anatomical Therapeutic Chemical Classification System definition of defined daily doses (DDD) per 1,000 patient-days to calculate the annual antibiotic consumption for 18 antibiotic groups. Chi-square linear-by-linear analysis was performed to evaluate antibiotic consumption trends for each group.RESULTS:
Average annual antibiotic consumption during 2001-2012 was 644.6 DDD/1,000 patient-days (standard deviation, 33.3 DDD/1,000 patient-days). Although no statistically significant change was observed during the study period, consumption of first- and second-generation cephalosporins, and aminoglycosides was significantly decreased, while that of beta-lactam/beta-lactamase inhibitors, fourth-generation cephalosporins, carbapenem, glycopeptide, linezolid, colistin, and quinolone increased significantly.CONCLUSION:
The total amount of prescribed antibiotics did not change, but the use of broad-spectrum antibiotics increased during the study period.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
World Health Organization
/
Cephalosporins
/
Classification
/
Colistin
/
Linezolid
/
Aminoglycosides
/
Hospitals, University
/
Korea
/
Anti-Bacterial Agents
Limits:
Adult
/
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Korean Journal of Nosocomial Infection Control
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS