Intrathecal injection of magnesium sulfate: shivering prevention during cesarean section: a randomized, double-blinded, controlled study / 대한마취과학회지
Korean Journal of Anesthesiology
;
: 293-298, 2013.
Article
in English
| WPRIM
| ID: wpr-100106
ABSTRACT
BACKGROUND:
Regional anesthesia is known to significantly impair thermoregulation and predispose patients to hypothermia. We hypothesized that the addition of an intrathecal injection of magnesium sulfate (MgSO4) to bupivacaine would improve perioperative shivering in female patients undergoing elective caesarean section.METHODS:
In a block-randomized, double-blinded, controlled trial 72 patients scheduled for elective caesarean section with spinal anesthesia were separated into two groups. In the treatment group, 2 ml of 0.5% bupivacaine plus 25 mg MgSO4 (0.5 ml) were injected intrathecally, and in the control group 2 ml of 0.5% bupivacaine plus 0.5 ml normal saline were injected intrathecally. Core temperature was measured before and after drug injection at predetermined intervals. Sedation was graded using the Ramsay sedation scale.RESULTS:
No significant intergroup differences in appearance of shivering were seen immediately or at 5, 30, 40, 50, 60, and 90 min after block administration. However, at 10, 15, and 20 min post block, there was a significant difference in shivering. The group administered MgSO4 showed lower shivering grades compared with the control group. Core temperature was significantly reduced in the MgSO4 group compared to the normal saline group 30 min after blocking.CONCLUSIONS:
Intrathecal injection of MgSO4 improved perioperative shivering in female patients undergoing elective caesarean section.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Shivering
/
Body Temperature Regulation
/
Injections, Spinal
/
Bupivacaine
/
Cesarean Section
/
Hypothermia
/
Anesthesia, Conduction
/
Anesthesia, Spinal
/
Magnesium Sulfate
Type of study:
Controlled clinical trial
Limits:
Female
/
Humans
/
Pregnancy
Language:
English
Journal:
Korean Journal of Anesthesiology
Year:
2013
Type:
Article
Similar
MEDLINE
...
LILACS
LIS