Primary Antiphospholipid Antibody Syndrome: Neuro radiologic Findings in 11 Patients
Korean Journal of Radiology
;
: 5-10, 2000.
Article
in English
| WPRIM
| ID: wpr-100201
ABSTRACT
OBJECTIVE:
To describe the neuroradiologic findings of primary antiphospholipid antibody syndrome (PAPS). MATERIALS ANDMETHODS:
During a recent two-year period, abnormally elevated antiphospholipid antibodies were detected in a total of 751 patients. In any cases in which risk factors for stroke were detected-hypertension, diabetes mellitus, hyperlipidemia, smoking, and the presence of SLE or other connective tissue diseases-PAPS was not diagnosed. Neuroradiologic studies were performed in 11 of 32 patients with PAPS. We retrospectively reviewed brain CT (n = 7), MR (n = 8), and cerebral angiography (n = 8) in 11 patients with special attention to the presence of brain parenchymal lesions and cerebral arterial or venous abnormalities.RESULTS:
CT or MR findings of PAPS included nonspecific multiple hyper-inten-sity foci in deep white matter on T2-weighted images (5/11), a large infarct in the territory of the middle cerebral artery (4/11), diffuse cortical atrophy (2/11), focal hemorrhage (2/11), and dural sinus thrombosis (1/11). Angiographic findings were normal (5/8) or reflected either occlusion of a large cerebral artery (2/8) or dural sinus thrombosis (1/8).CONCLUSION:
Neuroradiologic findings of PAPS are nonspecific but in young or middle-aged adults who show the above mentioned CT or MR findings, and in whom risk factors for stroke are not present, the condition should be suspected.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Brain
/
Magnetic Resonance Imaging
/
Cerebral Angiography
/
Tomography, X-Ray Computed
/
Risk Factors
/
Antiphospholipid Syndrome
/
Middle Aged
Type of study:
Diagnostic study
/
Etiology study
/
Risk factors
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
English
Journal:
Korean Journal of Radiology
Year:
2000
Type:
Article
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