The solid predominant subtype as an independent risk factor for recurrence in patients with pathologic stage I lung adenocarcinoma / 고신대학교의과대학학술지
Kosin Medical Journal
;
: 117-125, 2023.
Article
in English
| WPRIM
| ID: wpr-1002481
ABSTRACT
Background@#Increasingly many patients have been diagnosed with stage I adenocarcinoma due to the use of low-dose chest computed tomography for lung cancer screening. Therefore, this study aimed to analyze tumor recurrence based on the predominant subtype in patients with stage I lung adenocarcinoma who underwent lobectomy. @*Methods@#We retrospectively analyzed 114 patients who underwent lobectomy for pathologic stage I lung adenocarcinoma from June 2001 to July 2019. @*Results@#In univariate analyses, significant factors were current smoking at the time of surgery (p=0.029), pathologic tumor size (p=0.006), central tumor location (p=0.003), maximum standardized uptake value on positron emission tomography-computed tomography (p=0.001), and the solid predominant subtype (p=0.012). In the multivariate analysis, only the solid predominant subtype (hazard ratio, 9.702; 95% confidence interval, 1.179–79.874; p=0.035) was an independent risk factor. @*Conclusions@#If the solid subtype is predominant in pathologic findings, adjuvant chemotherapy after standard surgical resection may be considered to help reduce the risk of tumor recurrence and increase survival.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
English
Journal:
Kosin Medical Journal
Year:
2023
Type:
Article
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