A Rare Case of Methotrexate Induced Pancreatitis in Ectopic Pregnancy / 이화의대지
The Ewha Medical Journal
;
: e3-2023.
Article
in English
| WPRIM
| ID: wpr-1002846
ABSTRACT
Ectopic pregnancy (EP) refers to blastocyst implantation outside the uterine endometrium. EP is major cause of maternal morbidity and mortality. Treatment options include surgery, medical therapy with methotrexate, or expectant management. Methotrexate is the primary regimen used in cases of early, unruptured ectopic pregnancies. Most side effects of methotrexate are minor, including nausea, vomiting, abdominal discomfort, and photosensitive skin reaction. Serious side effects, including bone marrow suppression, and pulmonary fibrosis, are invariably observed when methotrexate is administered in high doses with frequent dosing intervals, in chemotherapeutic protocols for malignancy. These side effects are uncommon with the doses used to treat ectopic pregnancies. Since cases of methotrexate-induced pancreatitis are rare, we report a case of pancreatitis in a patient with EP treated with methotrexate and expect to consider pancreatitis as a side effect of methotrexate in a patient with upper abdominal pain undergoing methotrexate chemotherapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
English
Journal:
The Ewha Medical Journal
Year:
2023
Type:
Article
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