Progress of researches on molecular mechanisms underlying helminth infection-mediated type 1/2 host immune responses / 中国血吸虫病防治杂志
Chinese Journal of Schistosomiasis Control
;
(6): 534-538, 2023.
Article
in Chinese
| WPRIM
| ID: wpr-1003614
ABSTRACT
Helminth infections are widespread worldwide, and pose a serious threat to human health and animal husbandry development. Understanding of helminth-host interactions is critical to effective control and ultimate eradication of helminthiasis. Following host infections, helminth infections firstly initiate innate immune responses and then mediate adaptive immune responses. Type 1 immune responses are predominant at early stage of helminth infections, which mainly play anti-infective actions, and type 2 immune responses are predominant at late stage of infections, which are associated with helminth immune evasion and aggravation of tissue damages. This review summarizes the progress of researches on type 1/2 immune responses-associated signaling pathways mediated by helminth infections in hosts.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Schistosomiasis Control
Year:
2023
Type:
Article
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