Effects of sevoflurane and propofol on coagulation function and postoperative recovery in children with congenital dislocation of hip joint / 中国输血杂志

ABSTRACT

【Objective】 To investigate the effects of sevoflurane and propofol on coagulation function and postoperative recovery in children with congenital dislocation of hip joint. 【Methods】 A total of 92 children with congenital dislocation of hip joint admitted to our hospital from June 2017 to June 2020 were studied. According to the random sampling method, the subjects were divided into sevoflurane group and propofol group with 46 cases in each group, Sevoflurane and propofol were administered to the sevoflurane group and the propofol group during anesthesia induction and maintenance, respectively, The changes of hemodynamic index, body temperature, coagulation function before and after operation, postoperative outcome and the incidence of complication were compared between the two groups at different time points of anesthesia. 【Results】 Few significant differences in SBP, DBP, HR at different time points of anesthesia were noticed between the two groups (P>0.05). The body temperature of children in the study group at T1, T2 and T3 was significantly lower than that of the sevoflurane group (P0.05) between the two groups. In the propofol group, there was no statistically significant difference in coagulation indexes before and after surgery (P>0.05), while in the sevoflurane group, all coagulation indexes after surgery were significantly higher than before surgery (P<0.05). The retention time, wake time, extubation time and hospital stay length of the children in the propofol group were significantly shorter than those in the sevoflurane group (P<0.05). The incidence of complication in the propofol group was significantly lower than that of the sevoflurane group (P<0.05). 【Conclusion】 Compared with sevoflurane, propofol anesthesia maintenance is more beneficial to reduce the incidence of intraoperative hypothermia, and does not affect the hemodynamic indexes and coagulation function of the body, which is of positive significance for promoting postoperative anesthesia recovery and shortening the recovery time of children with congenital dislocation of hip joint.