Outcome of Early Diagnos is and Hemodialys is in Acute Renal Failure due to Metformin-associated Lactic Acidosis in Elderly Type 2 Diabetes Mellitus Patient
Journal of the Korean Geriatrics Society
; : 115-118, 2004.
Article
in Ko
| WPRIM
| ID: wpr-100750
Responsible library:
WPRO
ABSTRACT
Metformin is a biguanide oral hypoglycemic agent commonly used in the treatment of diabetes mellitus. Metfofmin is excreated largely by the kidney and binds only negligibly to plasma proteins. Toxicity is usually seen when metformin is prescribed to patients with renal insufficiency. Lactic acidosis in diabetics on metformin therapy is rare but still associated with poor prognosis. For an early diagnosis, clinical symptoms of intoxication should be well known by physicians and patients. First-line therapy for correction of lactic acidosis and effective elimination of metformin is bicarbonate hemodialysis. We report a case of acute renal failure due to metformin-associated lactic acidosis in elderly type 2 diabetes mellitus patient and she was successfully treated by hemodialysis with bicarbonate buffer.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Prognosis
/
Acidosis, Lactic
/
Blood Proteins
/
Renal Dialysis
/
Early Diagnosis
/
Diabetes Mellitus
/
Diabetes Mellitus, Type 2
/
Renal Insufficiency
/
Acute Kidney Injury
/
Kidney
Type of study:
Diagnostic_studies
/
Prognostic_studies
/
Screening_studies
Limits:
Aged
/
Humans
Language:
Ko
Journal:
Journal of the Korean Geriatrics Society
Year:
2004
Type:
Article