A new antimicrobial isobenzoisofuran compound from Cassia pumila / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 896-898, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-1008516
ABSTRACT
A new isobenzoisofuran(1) has been isolated from the whole plant of Cassia pumila using various chromatographic techniques, including silica gel, Sephadex, MCI-gel resin, and RP-HPLC, and its structure was determined as 9-(2-hydroxyethyl)-2,2-dimethyl-2H-furo[3,4-g]chromen-6(8H)-one. This compound was also evaluated for its antibacterial activity. The results showed that it had prominent antibacterial activity with MIC_(90) value of(45.2±4.2) μg·mL~(-1) for methicillin resistant Staphylococcus aureus(MRSA) strain. This value was closed to that of levofloxacin [with MIC_(90) value(48.5±4.3) μg·mL~(-1)].
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plants, Medicinal
/
Benzofurans
/
Cassia
/
Microbial Sensitivity Tests
/
Methicillin-Resistant Staphylococcus aureus
/
Levofloxacin
/
Phytochemicals
/
Anti-Bacterial Agents
Language:
Chinese
Journal:
China Journal of Chinese Materia Medica
Year:
2020
Type:
Article
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