Recent research on the relationship between pulmonary microbiome and asthma endotypes in children / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 1078-1083, 2023.
Article
in Zh
| WPRIM
| ID: wpr-1009850
Responsible library:
WPRO
ABSTRACT
Bronchial asthma is not considered a singular disease, but rather a collection of syndromes with multiple phenotypes and mechanisms that involve various signaling pathways. It typically emerges during the preschool years, and its etiology is intricate and diverse. In recent years, the advancement of high-throughput sequencing technology has revealed that early alterations in lung microbiota may be associated with asthma incidence and progression. Moreover, significant variations in lung microbiota have been observed among different airway inflammation profiles, known as asthma endotypes. Hence, a comprehensive understanding of the characteristics of lung microbiota in children with asthma can aid in managing disease progression and improving long-term prognosis. Additionally, such insights may spark novel approaches to diagnosing and treating childhood asthma.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Phenotype
/
Asthma
/
Microbiota
/
Inflammation
/
Lung
Limits:
Child
/
Child, preschool
/
Humans
Language:
Zh
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2023
Type:
Article