Diagnostic significance and considerations of growth hormone stimulation testing and insulin-like growth factor 1 in growth hormone deficiency / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 1193-1197, 2023.
Article
in Zh
| WPRIM
| ID: wpr-1009869
Responsible library:
WPRO
ABSTRACT
The growth hormone (GH)/insulin-like growth factor 1 (IGF-1) axis is an essential component of the hypothalamic-pituitary growth hormone axis and plays a crucial role in childhood growth and development. Disruptions and abnormalities in the GH/IGF-1 signaling pathway and its pathways typically manifest as short stature in children. Children with short stature often undergo GH stimulation testing and IGF-1 level measurements to differentiate growth hormone deficiency (GHD) from other causes of growth delay. This article aims to analyze and elucidate the values of GH stimulation testing and IGF-1 measurement, providing reference for the diagnosis of GHD in children.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Insulin-Like Growth Factor I
/
Growth Hormone
/
Insulin-Like Growth Factor Binding Protein 3
/
Human Growth Hormone
/
Dwarfism, Pituitary
/
Insulin-Like Peptides
Limits:
Child
/
Humans
Language:
Zh
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2023
Type:
Article