Research Progress of Cancer-associated Fibroblasts in Hematolo- gic Malignancies --Review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1885-1889, 2023.
Article
in Chinese
| WPRIM
| ID: wpr-1010054
ABSTRACT
Cancer-associated fibroblasts (CAF) are a key component of the tumor microenvironment, which can secrete a variety of cytokines, chemokines and growth factors, directly and indirectly support cancer cells, also alter the immune cellular environment by inhibiting the activity of immune effector cells and recruiting immunosuppressive cells, thereby allowing cancer cells to evade immune surveillance. CAF has been proven to be associated with the development, progression, and poor prognosis of solid tumors. However, the role of CAF in hematological malignancies is still unclear. This article reviews the research progress of CAF in hematological malignancies.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Hematologic Neoplasms
/
Tumor Microenvironment
/
Fibroblasts
/
Cancer-Associated Fibroblasts
/
Neoplasms
Limits:
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2023
Type:
Article
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