Advances in pathophysiology, diagnosis and treatment of adult severe-associated thrombotic microangiopathy / 中华危重病急救医学
Chinese Critical Care Medicine
;
(12): 1335-1339, 2023.
Article
in Chinese
| WPRIM
| ID: wpr-1010950
ABSTRACT
Thrombotic microangiopathy (TMA) is a group of highly heterogeneous, acute and severe clinicopathological syndromes, characterized by microangiopathic hemolytic anemia (MAHA), thrombocytopenia and ischemic injury of end organs. TMA has the characteristics of dangerous condition, multiple organ involvement and high mortality. Patients with severe TMA need to be admitted to intensive care unit (ICU) for organ function support therapy. Early and rapid evaluation, differential diagnosis, and timely and effective treatment are the key to improve the prognosis of TMA patients. Here, we review the pathophysiological changes, diagnosis differential diagnosis, and treatment of the severe TMA in adult.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Purpura, Thrombotic Thrombocytopenic
/
Treatment Outcome
/
Diagnosis, Differential
/
Thrombotic Microangiopathies
/
Anemia, Hemolytic
Limits:
Adult
/
Humans
Language:
Chinese
Journal:
Chinese Critical Care Medicine
Year:
2023
Type:
Article
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