A Soft Tissue Perineurioma and a Hybrid Tumor of Perineurioma and Schwannoma
Korean Journal of Pathology
;
: 75-78, 2012.
Article
in English
| WPRIM
| ID: wpr-101116
ABSTRACT
Perineuriomas are composed of differentiated perineurial cells. Perineuriomas have been recently recognized by the immunoreactivity for epithelial membrane antigen (EMA). Microscopically, perineuriomas show proliferation of spindle cells with wavy nuclei and delicate elongated bipolar cytoplasmic processes. The tumor cells are usually negative for the S-100 protein. Ultrastructurally, perineurial cells reveal slender, nontapered processes containing pinocytic vesicles and discontinuous basal lamina. Interestingly, hybrid tumors of benign peripheral nerve sheath tumor (PNST) have been recently reported by using immunohistochemical and ultrastructural investigations. Herein, we report a case of soft tissue perineurioma arising in the skin of a 56-year-old female; another case of a hybrid tumor of perineurioma and schwannoma in the posterior mediastinum occurred in a 53-year-old male, which is the first case of the hybrid PNST tumor reported in Korea.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peripheral Nerves
/
Skin
/
Basement Membrane
/
S100 Proteins
/
Chimera
/
Nerve Sheath Neoplasms
/
Mucin-1
/
Cytoplasm
/
Korea
/
Mediastinum
Limits:
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
Korean Journal of Pathology
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS