Lymphomatoid gastropathy: one case report and literatures review / 中华血液学杂志
Chinese Journal of Hematology
;
(12): 937-941, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-1011892
ABSTRACT
Objective:
To report the first case of lymphomatoid gastropathy in China, and to demonstrate the clinical characteristics, diagnostic approach, treatment and prognosis in this kind of patients.Methods:
One patient was diagnosed as lymphomatoid gastropathy at Peking Union Medical College Hospital, and her clinical characteristics, lab data, treatment and follow-up outcomes were reviewed.Results:
A case of a 51-year-old female was presented, who underwent esophagogastroduodenoscopy (EGD) due to slight epigastric discomfort. EGD revealed multiple ulcers and erosions. Biopsies showed atypical lymphocytes infiltration with CD3(+), CD56(+), CD20(-), CD8(-), TIA(+), Granzyme B(-) and Ki-67 (75%). Epstein-Barr virus-encoded RNA in situ hybridization was negative. Four months later, repeated EGD examination showed regression of the lesions without specific treatment.Conclusion:
Lymphomatoid gastropathy was a unique disease entity mimicking NK/T-cell lymphomas in pathology, with the quite different profile of treatment and prognosis. It's important to consider this issue during the differential diagnosis to avoid any excessive treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Stomach Diseases
/
Biopsy
/
China
/
Immunophenotyping
/
Lymphoma, T-Cell, Peripheral
/
In Situ Hybridization
/
Lymphatic Diseases
Limits:
Female
/
Humans
Country/Region as subject:
Asia
Language:
Chinese
Journal:
Chinese Journal of Hematology
Year:
2018
Type:
Article
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