The Early Detection of Recurrence of Malignant Peripheral Nerve Sheath Tumor by Frequent Magnetic Resonance Imaging
Journal of Korean Neurosurgical Society
;
: 51-54, 2010.
Article
in English
| WPRIM
| ID: wpr-101193
ABSTRACT
Surgery has a key role in the treatment of malignant peripheral nerve sheath tumors (MPNSTs), but the resectability of paraspinal MPNSTs is only 20%. Therefore, spinal MPNSTs show frequent recurrence and poor prognosis. Local recurrence is much more common than metastasis for MPNSTs, and surgery still has a key role in the treatment of local recurrence. Therefore, it is important that recurrence must be detected before resectability is lost. However, no evidence-based follow-up protocol has been established for MPNST. The authors performed gross total resection in a 34-year-old woman presented with thoracic MPNST. Adjuvant radiotherapy and chemotherapy were not administered since these adjuvant therapies generally do not improve survival in MPNST and may cause additional neurovascular damage. Instead, the authors monitored the primary site every 3 months using magnetic resonance imaging to detect local recurrence at the earliest opportunity. The tumor recurred locally on two occasions without overt symptoms at 21 and 24 months postoperatively. These recurrences were treated successfully by gross total removal.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peripheral Nerves
/
Prognosis
/
Recurrence
/
Magnetic Resonance Imaging
/
Magnetic Resonance Spectroscopy
/
Follow-Up Studies
/
Nerve Sheath Neoplasms
/
Radiotherapy, Adjuvant
/
Magnets
/
Magnetics
Type of study:
Diagnostic study
/
Practice guideline
/
Observational study
/
Prognostic study
/
Screening study
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
Journal of Korean Neurosurgical Society
Year:
2010
Type:
Article
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