Fecal microbiota transplantation for patients with refractory diarrhea after allogeneic hematopoietic stem cell transplantation / 中华血液学杂志
Chinese Journal of Hematology
;
(12): 853-855, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-1012080
ABSTRACT
Objective:
To explore the availability and safety of fecal microbiota transplantation for patients with refractory diarrhea after allogeneic hematopoietic stem cell transplantation (allo-HSCT) .Methods:
Four acute leukemia patients suffered from refractory diarrhea after allo-HSCT. One of them was refractory intestinal infection, the others were intestinal graft versus host disease. One or two doses of fecal microbiota, 3.4-6.0 U for one dose, were infused via nasal-jejunal tube. The curative effect and side effects were reviewed.Results:
Three cases achieved complete remission while 1 was stable disease. The side effects included fever, abdominal pain and diarrhea, which all were Ⅰ grade.Conclusion:
Fecal microbiota transplantation was effective and safe for refractory diarrhea after allo-HSCT.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Leukemia, Myeloid, Acute
/
Hematopoietic Stem Cell Transplantation
/
Diarrhea
/
Fecal Microbiota Transplantation
/
Graft vs Host Disease
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Hematology
Year:
2019
Type:
Article
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