More attention for high-risk pathological features for stage Ⅱ colorectal cancer required / 中华病理学杂志
Chinese Journal of Pathology
;
(12): 773-777, 2023.
Article
in Chinese
| WPRIM
| ID: wpr-1012306
ABSTRACT
Stage Ⅱ (T3-4N0M0) accounts for 25% of colorectal cancer and five-year survival is between 70% and 80%. However, 25% of patients develop distant metastases and have a survival rate similar to that of stage Ⅲ disease. However, whether or not to give adjuvant chemotherapy is still a controversial issue. As a result, there has been a lot of interest in the identification of the pathological factors underlying the poor prognosis associated with this stage, in order to establish a firmer basis for the administration of adjuvant chemotherapy. But not all high-risk factors are equal for stage Ⅱ colorectal cancer, variability still exists in the management and outcomes of high-risk patients. Here be introduced and commented on thinking and understanding about its controversy and evolution for the attention of the working pathologist and gastroenterologist doctors.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Prognosis
/
Colorectal Neoplasms
/
Antineoplastic Combined Chemotherapy Protocols
/
Risk Factors
/
Chemotherapy, Adjuvant
/
Neoplasm Staging
Limits:
Humans
Language:
Chinese
Journal:
Chinese Journal of Pathology
Year:
2023
Type:
Article
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