A fatal case of hepatitis B virus (HBV) reactivation during long-term, very-low-dose steroid treatment in an inactive HBV carrier
Clinical and Molecular Hepatology
;
: 225-228, 2012.
Article
in English
| WPRIM
| ID: wpr-101274
ABSTRACT
Hepatitis B virus (HBV) may be reactivated after chemotherapy or immunosuppressive therapy, and therefore administration of antiviral agents before such treatment is recommended. Most reported cases of reactivation are associated with high doses of immunosuppressive agents or combination therapy. We present a case of a previously inactive HBV carrier with an acute severe flare-up during a long-term, very-low-dose (2.5 mg/day) steroid treatment for rheumatoid arthritis. We suggest that even a minimal dose of single-regimen oral steroid can cause reactivation of indolent, inactive HBV.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Antiviral Agents
/
Arthritis, Rheumatoid
/
Steroids
/
Virus Activation
/
DNA, Viral
/
Tomography, X-Ray Computed
/
Hepatitis B virus
/
Treatment Outcome
/
Hepatitis B
/
Hepatitis B Surface Antigens
Limits:
Aged
/
Aged80
/
Female
/
Humans
Language:
English
Journal:
Clinical and Molecular Hepatology
Year:
2012
Type:
Article
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