Effect of LncRNA p21 regulating Hippo-YAP signaling pathway on formation of abdominal aortic aneurysm in mice and its mechanism

Xiao CHEN; Jin-Jun WANG; Lin-Lin ZHANG; Lian-Lian GUO; Zhong-Wang ZHANG; Juan-Zi ZHANG

Effect of LncRNA p21 regulating Hippo-YAP signaling pathway on formation of abdominal aortic aneurysm in mice and its mechanism / 中国药理学通报

Xiao CHEN; Jin-Jun WANG; Lin-Lin ZHANG; Lian-Lian GUO; Zhong-Wang ZHANG; Juan-Zi ZHANG.

Chinese Pharmacological Bulletin ; (12): 55-62, 2024.

Article in Chinese | WPRIM | ID: wpr-1013592

ABSTRACT

ABSTRACT

Aim To investigate the effect of long non- coding RNA p21 (LncRNA p21) regulating Hippo- Yes-associated protein (Hippo-YAP) signaling pathway on the formation of abdominal aortic aneurysm (AAA) in mice. Methods C57BL/6 ApoE

abdominal aortic aneurysm; ap-optosis; Hippo-Yes-related protein pathway; long non-coding RNA p21; mice; proliferation

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Pharmacological Bulletin Year: 2024 Type: Article