Study on mechanism of Hippo/YAP pathway inhibition by salvianolic acid B in HuH-7 cells

Xin-Mei YU; Li-Li LI; Yan YANG; Ao ZHANG; Jie DENG

Study on mechanism of Hippo/YAP pathway inhibition by salvianolic acid B in HuH-7 cells / 中国药理学通报

Xin-Mei YU; Li-Li LI; Yan YANG; Ao ZHANG; Jie DENG.

Chinese Pharmacological Bulletin ; (12): 106-113, 2024.

Article in Chinese | WPRIM | ID: wpr-1013607

ABSTRACT

ABSTRACT

Aim To investigate whether salvianolic acid B ( Sal B) has inhibitory effect on hepatoma HuH- 7 cells and explore whether it works via Hippo/YAP signaling pathway. Methods HuH-7 cells were induced by TGF-β1 (9 pmol · L

HCC; Hippo/YAP; HuH-7; Sal B; TGF-ßl; XMU-MP-1

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Pharmacological Bulletin Year: 2024 Type: Article