Ginsenoside Rgl inhibits neuronal ferroptosis caused by ischemic stroke through activating of Nrf2/xCT/GPX4 axis / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12): 1905-1913, 2023.
Article
in Chinese
| WPRIM
| ID: wpr-1013686
ABSTRACT
Aim To study the inhibitory effect of ginsenoside Rgl on neuronal ferroptosis after ischemic stroke and its mechanism. Methods A model of oxygen glucose deprivation/reoxygenation (OGD/R) was established in HT22 cells, and the effect of Rgl on the viability of HT22 cells after OGD/R injury was detected by CCK-8. The effect of Rgl on ferroptosis in HT22 cells after OGD/R injury was detected by the test of ferroptosis markers GSH/GSSG, SOD, MDA, and Fe
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
2023
Type:
Article
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