Mechanism of heroin promoting addiction and relapse in progeny of male rats by inhibiting promoter methylation of imprinted gene H19 by down-regulating DNMT3a / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 1515-1521, 2023.
Article
in Zh
| WPRIM
| ID: wpr-1013748
Responsible library:
WPRO
ABSTRACT
Aim To investigate the effect of heroin use in male rats of F0 generation on heroin addiction and relapse in rats of Fl generation and the underlying mechanism. Methods Male rats of F0 generation were treated with different doses of heroin (1, 3, 9 mg • kg
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Pharmacological Bulletin
Year:
2023
Type:
Article