Research progress on antidepressant effects of melatonin and its receptor agonists / 中国药理学通报
Chinese Pharmacological Bulletin
; (12): 343-346, 2022.
Article
in Zh
| WPRIM
| ID: wpr-1014132
Responsible library:
WPRO
ABSTRACT
Depression, a chronic syndrome with significant and lasting depression and sleep disturbance, is the most common mental disorder.Recent studies have shown that melatonin plays an important role in the occurrence and development of depression.rI1iis review describes the antidepressant effects of melatonin from HPA axis, cytokines, neurosynaptic plasticity and monoamine neurotransmitters, and summarizes the melatonin receptor agonists agomelatine, ramelteon and piromelatine antidepressant effects.A theoretical basis is expected to provide a reference for the study of melatonin's antidepressant mechanism.
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WPRIM
Language:
Zh
Journal:
Chinese Pharmacological Bulletin
Year:
2022
Type:
Article