Effect of Li-Zhong-Tang on gastric ulcer in rats based on Raf/MEK/ERK signaling pathway and its mechanism / 中国药理学通报
Chinese Pharmacological Bulletin
;
(12): 1291-1298, 2021.
Article
in Chinese
| WPRIM
| ID: wpr-1014373
ABSTRACT
Aim To investigate the effect of Li-Zhong-Tang (LZT) in the treatment of gastric ulcer (GU) with pattern of spleen-stomach vacuity cold in rats based on Raf/MEK/ERK signaling pathway and the underlying molecular mechanism. Methods SD rats were randomly divided into normal group, GU model group, esomeprazole (ESO) group, LZT low dose and high dose groups. The morphological changes of gastric mucosa were observed by naked eyes and HE staining. The activities of gastric acid and pepsin were measured. The contents of prostaglandin E
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmacological Bulletin
Year:
2021
Type:
Article
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