Autophagy and intrauterine growth retardation / 中国药理学通报

ABSTRACT

Autophagy is involved in the development of multiple organs, and abnormal autophagy can affect the growth and development of the body. Intrauterine growth retardation (IUGR) is one of the most common developmental toxicities, which can lead to increased perinatal morbidity and mortality of offspring, and the damage continues to cause adult susceptibility to a variety of chronic diseases after birth. This review mainly reviewed the pathogenesis of autophagy and its relationship with IUGR, so as to provide a theoretical basis for the study of autophagy in IUGR-related diseases.