Migrasome: A New Cellular Organelle / 中国生物化学与分子生物学报

ABSTRACT

Migrasomes are newly discovered cellular organelles generated during cell migration. The process to generate migrasomes is named migracytosis. Migracytosis and migrasomes function in long term intracellular communications and are shown to be essential in zebrafish embryonic development. In this review, we summarized the current research progress on migrasome, including the molecular mechanisms involved in migrasome biogenesis and its physiological significance. We also reviewed the established protocols and tools for migrasome studies, which may help setting up standard in migrasome field. In addition, we proposed the unsolved questions and potential directions of this emerging field, hoping more scientists from other field to be interested and to work on migrasomes.