Research Status of Exosomes and Pathogenesis of Inflammatory Bowel Disease / 胃肠病学
Chinese Journal of Gastroenterology
;
(12): 749-753, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-1016285
ABSTRACT
Exosomes are extracellular vesicles with a diameter of 30-150 nm, which exist in multi-vesicular bodies in the form of intraluminal vesicles. Exosomes can be secreted by a variety of immune cells. Studies have shown that exosomes might play an important role in IBD through their components, such as annexin-A1 (ANXA1), the miRNAs and lipids. As a carrier of antigen presentation, it can affect the signaling pathways related to IBD, regulate the immune response and intestinal homeostasis. This article reviewed the relationship between exosomes and IBD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Gastroenterology
Year:
2020
Type:
Article
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