Research Progress on Related Genes of Gastroesophageal Reflux Disease / 胃肠病学
Chinese Journal of Gastroenterology
;
(12): 631-634, 2020.
Article
in Chinese
| WPRIM
| ID: wpr-1016315
ABSTRACT
Gastroesophageal reflux disease (GERD) is a common disease with complex pathogenesis and poor efficacy of traditional treatments. With the development of molecular biotechnology, it is demonstrated that gene polymorphisms such as IL-1B, IL-1RN, PAR-2, and GSTP1 can increase disease susceptibility, while COX-2, CDX-2, MMPs, EGF and other genes can promote the development of GERD into Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC). The study of genetics will contribute to the prevention and treatment of the disease. This article reviewed the role of related genes in the occurrence, development and carcinogenesis of GERD.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Journal of Gastroenterology
Year:
2020
Type:
Article
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