Guidelines of Prevention and Treatment for NSAID-related Peptic Ulcers / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 309-317, 2009.
Article
in Korean
| WPRIM
| ID: wpr-101885
ABSTRACT
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used medications in Korea. Gastrointestinal toxicity, including peptic ulcer, is a common adverse effect of NSAIDs. Risk factors for NSAID-related peptic ulcer include a previous history of peptic ulcer, advanced age, high dose, concomitant use of corticosteroids, anticoagulants, other NSAIDs including low-dose aspirin. Preventive measure(s), such as COX-2 inhibitor, proton pump inhibitor or misoprostrol, should be done for patients requiring NSAID therapy who have high-risk factor(s) for peptic ulcer. Low dose aspirin also increases the risk of peptic ulcer, so preventive measure(s) should be done for high-risk patients. The eradication of Helicobacter pylori is recommended for high-risk NSAID-users. Treatment strategies for peptic ulcers in NSAID users are mostly the same for peptic ulcers in NSAID non-users.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Peptic Ulcer
/
Anti-Inflammatory Agents, Non-Steroidal
/
Aspirin
/
Helicobacter pylori
/
Helicobacter Infections
/
Misoprostol
/
Cyclooxygenase 2 Inhibitors
/
Proton Pump Inhibitors
/
Anti-Ulcer Agents
/
Anticoagulants
Type of study:
Practice guideline
Limits:
Humans
Language:
Korean
Journal:
The Korean Journal of Gastroenterology
Year:
2009
Type:
Article
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