Research progress on biomarkers for diagnosis and treatment of neurally mediated syncope in children / 中国小儿急救医学

ABSTRACT

Vasovagal syncope (VVS) and postural orthostatic tachycardia syndrome (POTS) are the most common types of neurally mediated syncope, which is prevalent in school-age children and adolescents, seriously affecting their daily life and learning quality, and increasing the risk of accidental injury due to syncope.Because the clinical signs of these two diseases are very similar, diagnosis between VVS and POTS can easily be confused, and the pathogenesis of these two is not the same, the curative effect of empirical treatment is not very ideal.Therefore, finding a sensitive and reliable method for differential diagnosis and formulating individualized treatment plans have become an urgent clinical need in pediatrics syncope.In recent years, pediatricians utilizing biomarkers for study on differentiating VVS from POTS and predicting individualized treatment outcomes have made significant progress, thus promoting the precise treatment of syncope in children.