Primary Sjogren's Syndrome Presenting with Rapidly Progressive Cognitive Impairment
Journal of Rheumatic Diseases
;
: 336-341, 2013.
Article
in Korean
| WPRIM
| ID: wpr-102287
ABSTRACT
Primary Sjogren's syndrome (pSS) is characterized by chronic inflammation and dysfunction in exocrine organs; however, it also has protean clinical features, including neuropsychiatric symptoms. A major neurological manifestation is peripheral neuropathy and involvement of the central nervous system is uncommonly described in pSS. A 52-year-old female was admitted because of depression, dysarthria, gait abnormality, and memory disturbance, which had developed over two months, and was diagnosed as pSS. She was treated successfully with high-dose glucocorticoid and cyclophosphamide pulse therapy without recurrence during the follow-up period of two years. Herein, we describe the first Korean case of pSS presenting with rapidly progressive cognitive impairment along with a review of the literature.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Sjogren's Syndrome
/
Central Nervous System
/
Follow-Up Studies
/
Peripheral Nervous System Diseases
/
Cyclophosphamide
/
Depression
/
Dysarthria
/
Gait
/
Inflammation
Type of study:
Observational study
/
Prognostic study
Limits:
Female
/
Humans
Language:
Korean
Journal:
Journal of Rheumatic Diseases
Year:
2013
Type:
Article
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