A Case of Microscopic Polyangiitis Associated with Paranasal Sinusitis and Pulmonary Hemorrhage / 대한신장학회잡지
Korean Journal of Nephrology
;
: 832-837, 2005.
Article
in Korean
| WPRIM
| ID: wpr-102320
ABSTRACT
Microscopic polyangiitis is a systemic small-vessel vasculitis primarily associated with necrotizing glomerulonephritis and pulmonary capillaritis. This disease is determined by clinical manifestation, ANCA, and involved organ or renal biopsy. We describe a 49-year-old female presenting with chronic postnasal drip, progressive dyspnea and abrupt hemoptysis. Her serum p-ANCA was postitive, but c- ANCA was negative. Her chest X-ray and chest CT scan showed pulmonary hemorrhage, and the renal biopsy specimen revealed crescentic glomerulonephritis. She was diagnosed as having an ANCA-associated vasculitis, and more specifically, a microscopic polyangiitis accompanied with paranasal sinusitis. She was treated with intravenous methylprednisolone pulse therapy, followed by prednisolone and cyclophosphamide per oral tablets. She showed rapid progression of renal failure and died from sepsis after 2 months of treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Sinusitis
/
Tablets
/
Thorax
/
Vasculitis
/
Biopsy
/
Methylprednisolone
/
Prednisolone
/
Tomography, X-Ray Computed
/
Sepsis
/
Antibodies, Antineutrophil Cytoplasmic
Limits:
Female
/
Humans
Language:
Korean
Journal:
Korean Journal of Nephrology
Year:
2005
Type:
Article
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