Comparison of Curative Effect between Nasogastric Tube Nutrition and Jejunal Nutrition in Patients with Severe Neurological Diseases / 医学研究杂志

ABSTRACT

Objective To explore the effects of nasogastric tube nutrition and jejunal nutrition on the complications and mortality in severe neurological diseases during hospitalization.Methods The clinical data of patients with severe neurological diseases admitted to Department of Intensive Care Unit,Wuhan Fourth Hospital from June 2020 to June 2022 were analyzed retrospectively.Patients were di-vided into nasogastric tube nutrition group and jejunal nutrition group according to enteral nutrition methods.The propensity score matc-hing(PSM)was used to equalize the baseline data of the two groups,and the differences in complications,mortality,hospitalization costs,and mean length of stay between two groups were compared.Results There were no significant differences in baseline data be-tween the two groups after PSM(P>0.05).There were also no significant differences in complication rate and mortality between the na-sogastric tube nutrition group and the jejunal nutrition group(P>0.05).Further univariate and multivariate regression Logistic analysis showed that age(OR =1.135,P =0.001),acute physiology and chronic health evaluation Ⅱscore(APACHEⅡ score,OR =1.147,P<0.001)and blood urea nitrogen level(OR = 1.135,P = 0.001)might be the key factors affecting the prognosis of patients with severe neurological diseases.Conclusion Enteral nutrition had no significant effect on the incidence of complications and mortality during hos-pitalization in patients with severe neurocritical diseases,elderly patients,higher levels of APACHE Ⅱ score and blood urea nitrogen were independent risk factors for mortality patients with severe neurological diseases.