A Phase Contrast Microscopic Study on the Induction of Cellular Deformation in Mast Cells
Yonsei Medical Journal
;
: 1-6, 1966.
Article
in English
| WPRIM
| ID: wpr-102487
ABSTRACT
The influence of colchicine, colcemid, ginseng-alcohol extract, saponin, garlic alcohol-ether extract, and X-irradiation on free floating peritoneal mast cells were studied in rats by means of a phase contrast microscope. After the intraperitoneal injection of colchicine or colcemid the mast cells of the albino rat peritoneal fluid show an altered morphology. Ginseng-alcohol extract, allicin extracted from garlic, and X-irradiation do not elicit this cytological response.Mast cells exposed to saponin exhibit a severe destruction and degranulation. The relation of the mast cell-damaging agents, metabolic poisons, and X1-irradiation to the mast cell response is discussed with reference to the morphological changes. These are compared with the data of Padawer (1960, 1966).
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Plants, Medicinal
/
Radiation Injuries, Experimental
/
Saponins
/
Plant Extracts
/
Colchicine
/
Microscopy, Phase-Contrast
/
Panax
/
Mast Cells
Limits:
Animals
Language:
English
Journal:
Yonsei Medical Journal
Year:
1966
Type:
Article
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