Drug rash with eosinophilia and systemic symptoms syndrome following cholestatic hepatitis A: a case report / 대한간학회지
The Korean Journal of Hepatology
;
: 84-88, 2012.
Article
in English
| WPRIM
| ID: wpr-102516
ABSTRACT
Hepatitis A virus (HAV) infections occur predominantly in children, and are usually self-limiting. However, 75-95% of the infections in adults are symptomatic (mostly with jaundice), with the illness symptoms usually persisting for a few weeks. Atypical manifestations include relapsing hepatitis, prolonged cholestasis, and complications involving renal injury. Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a severe, drug-induced hypersensitivity reaction characterized by skin rash, fever, lymph-node enlargement, and internal organ involvement. We describe a 22-year-old male who presented with acute kidney injury and was diagnosed with prolonged cholestatic hepatitis A. The patient also developed DRESS syndrome due to antibiotic and/or antiviral treatment. To our knowledge, this is the first report of histopathologically confirmed DRESS syndrome due to antibiotic and/or antiviral treatment following HAV infection with cholestatic features and renal injury.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Syndrome
/
DNA, Viral
/
Immunoglobulins
/
Hydrocortisone
/
Ganciclovir
/
Cefotaxime
/
Cholestasis
/
Cytomegalovirus Infections
/
Cytomegalovirus
/
Eosinophilia
Type of study:
Diagnostic study
Limits:
Humans
/
Male
Language:
English
Journal:
The Korean Journal of Hepatology
Year:
2012
Type:
Article
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