Repeated Paradoxical Aggravation of Preexisting Psoriasis during Infliximab Treatment for Crohn's Disease
Annals of Dermatology
;
: 60-62, 2009.
Article
in English
| WPRIM
| ID: wpr-103063
ABSTRACT
As more rheumatologists and dermatologists have begun to use biological agents such as TNF-alpha blocker, they have confronted an unexpected complication psoriasis was paradoxically aggravated or induced by the TNF-alpha blocker. Although it is not a common complication of TNF-alpha blocker, this aggravation may be more common than previously thought. To our knowledge, most reports about TNF-alpha blocker-induced psoriasis have been limited to western countries while only a few cases have been reported in Korea and Japan. In addition, new onset of pustular psoriasis by TNF-alpha blocker has been reported more commonly than worsening of preexisting psoriasis. Now we report a patient whose preexisting psoriasis vulgaris was aggravated repeatedly after using the TNF-alpha blocker, infliximab, to control Crohn's disease, which is a rare rheumatologic disease in Korea.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Psoriasis
/
Crohn Disease
/
Tumor Necrosis Factor-alpha
/
Infliximab
/
Japan
/
Korea
/
Antibodies, Monoclonal
Limits:
Humans
Country/Region as subject:
Asia
Language:
English
Journal:
Annals of Dermatology
Year:
2009
Type:
Article
Similar
MEDLINE
...
LILACS
LIS