Difference of clinical characteristics and risk factors between young patients and senior patients with spontaneous brainstem hemorrhage / 中风与神经疾病杂志

ABSTRACT

@#Objective This study aimed to analyze the difference of clinical characteristics and risk factors for poor outcome between young patients and senior patients with spontaneous brainstem hemorrhage. Methods This was a retrospective study.The patients with spontaneous brainstem hemorrhage who presented to the Nanjing Drum Tower Hospital from January 2013 to January 2021 were enrolled in this study.They were divided into two groups:Youth group (18-59 years old) and Senior group (60-90 years old).General information and clinical data were collected.Univariate analysis was used to compare the clinical characteristics of the two groups,and multivariate logistic regression was used to analyze the independent risk factors for poor prognosis. Results A total of 202 eligible patients were enrolled in this study,including 136 patients in the Youth group and 66 patients in the Senior group.Univariate analysis of the clinical data from the two groups demonstrated that the prevalence of poor outcome,the proportion of male patients,coma on admission,surgery operation,complicated pneumonia and the average NIHSS score,volume of hematoma,DBP,TG were significantly higher in the Youth group than the Senior group (P<0.05).The average GCS score was remarkably lower in the Youth group(P<0.05).Early coma,low GCS score,high NIHSS score,large volume of hematoma,poor glycemic control,complicated pneumonia and Acinetobacter baumannii infection were risk factors for poor prognosis of both group.Multivariate logistic regression showed that low GCS score was an independent predictor for poor prognosis of both group. Conclusion Young patients with spontaneous brainstem hemorrhage had worse prognosis than elderly patients.Avoiding or effective control of risk factors might ameliorate the final outcome.